- New York City 8,584,629 people (2025) · Known for Statue of Liberty
- Los Angeles 3,869,089 people (2025) · Known for Hollywood and the film industry
- Chicago 2,731,585 people (2025) · Known for Skyscraper architecture
- Houston 2,397,315 people (2025) · Known for Energy industry and oil
- Washington, D.C. 693,645 people (2025) · Capital · Known for Seat of the U.S. federal government